+ /     


Биологический факультет БГУ - Кафедра биохимии.    

Department of Biochemistry.


Mihhail V. Sholukh


Mikhail V. Sholukh

Mailing address:

Dept. of Biochemistry, Belarusian State University, Nezhaleznasti Av., 4, 220030, Minsk, Belarus.
Tel.: +375 (0)17 209-58-97,
Fax: +375 (0)17 209-58-08,
E-mail: msholukhmail.ru

Education:

1979 Ph.D. in Biochemistry (Belarusian State University, Dissertation title: "The influence of relatively low dose of X-irradiation on adrenergic regulation of aspartate aminotransferase isozymes");

1971-1974 Department of Biochemistry, School of Biology, Belarusian State University, Minsk, Belarus (Post-Graduate Course);

1966-1971 School of Biology, Belarusian State University, Minsk, Belarus (5-year Education Diploma in Biochemistry and MSc Diploma).

Positions held:

1987- present:Leading Researcher, Head of Research Group (Department of Biochemistry, School of Biology, Belarusian State University, Minsk, Belarus);

1982-1987 : Senior Research Associate(Department of Biochemistry, School of Biology, Belarusian State University, Minsk, Belarus);

1974-1982 - Lecturer (Department of Biochemistry, School Of Biology, Belarusian State University, Minsk, Belarus).

Research interest:

Biochemistry and physiology of prostaglandins. Pharmacological approach.

Signal transduction. Molecular mechanisms.

Investigation of oxidative stress significance in protein inactivation, denaturation and aggregation.

Results of research are presented in 176 scientific publications.

Selected Publications:

1. Muronetz, V.I., Sholukh M.V., Korpela T. Use of Protein-Protein Interactions in Affinity Chromatography. Journal of Biochemical and Biophysical Methods.2001,49(1-3), p. 29-47. (Full text - 121 Kb)

2. Hubich A.I., Sholukh M.V. Biochemistry of “A” group prostaglandins // Biochemistry (Moscow), 2006, – т. 71. №3. – с.293-304.

3. Nikolay V. Golub, Kira A. Markossian, Mikhail V. Sholukh, Konstantin O. Muranov, Boris I. Kurganov// Study of kinetics of thermal aggregation of mitochondrial aspartate aminotransferase by dynamic light scattering. Protective effect of alpha-crystallin European Biophysics Journal. 2009. v. 38. p.547-556.

4. Sholukh M.V., Hubich A.I., F.S. Pashkovsky, Lakhvich F.A. Structural features of prostanoid analogues involved in hepatocytes protection against CCl4-induced injury // Prostaglandins @ Other lipid mediators. – 2010. – Vol. 93. – P. 134-142.

5. Kira A. Markossian, Nikolay V. Golub, Sergey Yu Kleymenov, Konstantin O. Muranov, Mikhail V. Sholukh, Boris I. Kurganov//Effect of α-cristallin on thermostability of mitochondrial aspartate aminotransferase. International Journal of Biological Macromolecules. –2009, v. 44, p. 441-446.

6.Hubich A. I., Lakhvich F.A., Sholukh M.V.// The mechanism of the rat liver cytochrome P4502E1 inhibition by the synthetic prostanoids of A-type. Prostaglandins & other Lipid mediators.-2009.v.89, p.16-19.

7.Golub N.V., Markosian K.A., Kasilovich N.V., Sholukh M.V., Orlov V.N., Kurganov B.I.//Themal inactivation, denaturation and aggregation of mitochondrial aspartate aminotransferase. Biophysical Chem. 2008.– v.135.–p.125-131.

8. Golub N.V., Markosian K.A., Sholukh M.V., Kasilovich N.V., Kleimionov S.Y., Ktvitski D., Kurganov B.I.// Heat-indused inactivation and denaturation of mitochondrial aspartate aminotransferase//. Doklady of Russian Akademii Nauk. 2007, Т. 415, № 5, С. 1–3.(In Russian)

9.Hubich A. I., Bondar A.Y., Kastsuik T.U., Kastsuik U.A., Lakhvich F.A., Sholukh M.V. Hepatoprotective action of prostaglandin A2 analogs under CCl4-induced liver injury in vitro. Hepatol. Res. – 2007. – v. 37. № 6. – P. 416-424.

10.Hubich A.I., Zheldakova T.A., Chernikhova T.V., Koroleva E.A., Lakhvich F.A., Sholukh M.V. Synthetic heteroprostanoids of A- and E-types as novel non-comprehensive inhibitirs of adenylyl cyclase in rat hepatocytes // Biochem. Biophys. Res. Commun. – 2006. – v. 341. – p. 357-362.

11.Irina N. Shalova, Regina A. Asryants, Mikhail V. Sholukh, Luciano Saso, Boris I. Kurganov, Vladimir I. Muronetz, Vladimir A. Izumrudov . Interaction of Polyanions with Basic Proteins, 2a Influence of Complexing Polyanions on the Thermoaggregation of Oligomeric Enzymes // Macromolecular Bioscience, 2005, v.5, p. 1184-1192.

12.Fedorovich S.V., Chubanov V.S., Sholukh M.V., Konev S.V. Influence of plasma membrane depolarization on cAMP level in rat brain synaptosomes//NeuroReport –1999, Vol.10, No 8, 1763-1765.


Page last updated: 15.03.2019 12:44

Следуйте за белым кроликом...

  

Go to Top Go to Top Go to Top 


Go to Main Page | © 2003-2019 L. Valentovich, P. Tumilovich | Copyright |